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Research Areas

Prof. Giovanni Martinotti’s scientific and clinical work focuses on three main research areas: treatment-resistant depression and innovative therapies, the use of psychedelics in psychiatry, and the study of addictions and new psychoactive substances. 

The three areas

Psychedelics in Psychiatry

Research on psilocybin and psychedelic-assisted therapies for treatment-resistant depression, in clinical and experimental settings.

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Treatment-Resistant Depression and Brain Stimulation

New treatments for depression that does not respond to conventional therapies: esketamine and brain stimulation (TMS).

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Addictions and New Psychoactive Substances

The study of substance use disorders, behavioral addictions, and new psychoactive substances (NPS).

A common approach

Treatment-resistant depression, psychedelics, and addictions may seem like distinct fields, but they share one question: how to treat the psychiatric conditions for which conventional tools are not enough. My work combines clinical research in real-world settings with new treatments…

Full Professor of Psychiatry
University of Chieti

Among the top 2% of the world’s most influential academic scientists
(according to Stanford University)

Brain Health Award
CINP. 2024

H-index 70
600+ publications

Frequently asked questions

Q. What does Prof. Giovanni Martinotti do?
A. He is a psychiatrist and researcher. His work focuses on three areas: psychedelics in psychiatry, treatment-resistant depression and innovative therapies, and addictions and new psychoactive substances.

Q. What are his main research areas?
A. Research on psychedelics such as psilocybin, innovative therapies for treatment-resistant depression (esketamine, brain stimulation), and the study of addictions and new psychoactive substances.

Q. What is the common thread of his work?
A. The search for new therapeutic approaches to the most complex psychiatric conditions, combining clinical research with practice.